Browsing A) Producción científica UCSC by Author "Zamorano, Francisca"

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Synthesis of cephalexin in organic medium at high substrate concentrations and low enzyme to substrate ratio

Illanes, Andrés; Altamirano, Claudia; Fuentes, M.; Zamorano, Francisca; Aguirre Céspedes, Carolina (2005)

The kinetically controlled synthesis of cephalexin (CEX) in ethylene glycol (EG) was previously optimized at moderate substrate concentrations and high enzyme to substrate ratio, obtaining yields close to stoichiometric. ...
Synthesis of cephalexin with immobilized penicillin acylase at very high substrate concentrations in fully aqueous medium

Aguirre Céspedes, Carolina; Wilson, Lorena; Corretea, Octavio; Tavernini, Luigini; Illanes, Andrés; Zamorano, Francisca (2007)

The presence of organic cosolvents was previously considered necessary to obtain high conversion yields in the synthesis of β-lactam antibiotics with immobilized penicillin acylase, and it is so when working at moderate ...