Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
Date
2009Author
Coria, Carolina
Cabello, Aurora
Tassara, Enzo
López Arcos, Eduardo
Rosales, Hugo
Pérez, Marcelo
Zavala, Claudia
Muñoz, Patricio
Orellana, Gabriel
Inostroza, María
Contreras, Lorena
Kirsten, Lilian
Publisher
ScieloDescription
Artículo de publicación ISIMetadata
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Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour.
Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was significantly lower among subjects that, immediately after the exposure, had a lead level over 48 μg/dl, compared with those that had a lead level below 43 μ g/dl (86.7 ±7.3 and 93 ±11.6 respectively). No subjects with high blood pressure or evidences of nephrotoxicity were detected. Conclusions: Subjects agedless than six years at the moment of lead exposure had a lower IQ when assessed ten years later (Rev Méd Chile 2009; 137: 1037-44).